Nomenclature of CD molecules from the Tenth Human Leucocyte Differentiation Antigen Workshop

Nomenclature of CD molecules from the Tenth Human Leucocyte Differentiation Antigen Workshop.

Kohler and Milstein’s 1 description of monoclonal antibodies (mAbs) in 1975 revolutionised immunology. With the advent of hybridoma technology, immunologists started to produce an ever increasing number of mAbs directed against leukocyte cell-surface molecules. Inevitably, several mAbs produced by different laboratories and given independent names recognised the same molecule. The First Interna...

CD molecules 2005: human cell differentiation molecules.

The immune system works through leukocytes interacting with each other, with other cells, with tissue matrices, with infectious agents, and with other antigens. These interactions are mediated by cell-surface glycoproteins and glycolipids. Antibodies against these leukocyte molecules have provided powerful tools for analysis of their structure, function, and distribution. Antibodies have been u...

CD Nomenclature 2015: Human Leukocyte Differentiation Antigen Workshops as a Driving Force in Immunology.

CD (cluster of differentiation) Ags are cell surface molecules expressed on leukocytes and other cells relevant for the immune system. CD nomenclature has been universally adopted by the scientific community and is officially approved by the International Union of Immunological Societies and sanctioned by the World Health Organization. It provides a unified designation system for mAbs, as well ...

CD antigens 1993: an updated nomenclature for clusters of differentiation on human cells. IUIS/WHO Subcommittee on CD Nomenclature.

The 5th International Workshop on Human Leukocyte Differentiation Antigens (Boston, USA, 3-7 November 1993) recommended the adoption of 48 new CD clusters and subclusters and the redefinition of 14 previously established clusters. The additions and changes made to the existing CD nomenclature are summarized in a Table.

Human Leucocyte Antigen Matching Strategy